陳 世彬
臨床神經研究團隊
姓名 陳 世彬
電子郵件 spchen2@vghtpe.gov.tw
POSITION TITLE/AFFILIATIONS 台北榮民總醫院神經內科主治醫師
台北榮民總醫院醫學研究部轉譯研究科主治醫師
台北榮民總醫院醫學科技大樓管理中心主任
國立陽明交通大學臨床醫學研究所教授
國立陽明交通大學神經科學研究所教授
國立陽明大學醫學系神經學科教授
中研院跨領域神經科學-國際研究生博士班學程 (TIGP-INS)副教授
EDUCATION/TRAINING 國立陽明大學醫學士
國立陽明大學臨床醫學研究所博士
哈佛醫學院麻州總醫院神經血管研究室博士後研究員
研究專長 臨床專長為頭痛、失智症、帕金森氏症及神經免疫疾病。
研究概況 研究興趣主要為頭痛病生理機轉研究，包括
1. 雷擊頭痛及可逆性腦血管收縮症候群之臨床、影像及分子生物學研究
2. 偏頭痛病生理機轉之生物標記、動物模式、腦連結體及基因體學研究
年度 論文名稱
2021 Fu-Jung Hsiao,* Wei-Ta Chen, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Hung-Yu Liu, Li-Ling Hope Pan, Shuu-Jiun Wan, Somatosensory Gating Responses are Associated with Prognosis in Patients with Migraine, Brain Sciences, 11, 2, pp166-
2021 Fu-Jung Hsiao, Wei-Ta Chen, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Hung-Yu Liu, Li-Ling Hope Pan, Gianluca Coppola, Shuu-Jiun Wang, Migraine chronification is associated with beta-band connectivity within the pain-related cortical regions: A magnetoencephalographic study, Pain
2020 Fu-Jung Hsiao,* Wei-Ta Chen, Hung-Yu Liu, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Li-Ling Hope Pan, Shuu-Jiun Wang, Individual Pain Sensitivity Is Associated With Resting-State Cortical Activities in Healthy Individuals but Not in Patients With Migraine: A Magnetoencephalography Study., The journal of headache and pain, 21, 1, pp133-
2018 Chen SP¶, Fuh JL¶, Chung MY¶, Lin YC, Liao YC, Wang YF, Hsu CL, Yang YC, Lin MW, Chiou JJ, Wang PJ, Chen PK, Fan PC, Wu JY, Chen YT, Kao LS*, Fann CS*, Wang SJ*. Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan. Cephalalgia 2018; 38: 466-75
2018 Chen SP,* Chou KH,¶ Fuh JL,¶ Huang YH, Huang CC, Lirng JF, Wang YF, Lin CP, Wang SJ.* Dynamic Changes in White Matter Hyperintensities in Reversible Cerebral Vasoconstriction Syndrome. JAMA Neurology 2018 in press (*Equal contribution; ¶Equal contribution)
2018 Chou TM, Chen SP*. Animal Models of Chronic Migraine. Current Pain and Headache Reports. 2018 in press
2017 Chen SP, Qin T, Seidel JL, Zheng Y, Eikermann M, Ferrari MD, van den Maagdenberg AM., Moskowitz MA, Ayata C, Eikermann-Haerter K. Inhibition of the P2X7-pannexin 1 complex suppresses spreading depolarization and neuroinflammation. Brain 2017; 140:1643-1656
2017 Chen SP, Ayata C.* Novel Therapeutic Targets against Spreading Depression. Headache 2017;57:1340-1358
2016 Chen SP,* Ay I, Lopes de Morais A, Qin T, Zheng Y, Sadeghian H, Oka F, Simon B, Eikermann-Haerter K, Ayata C. Vagus nerve stimulation inhibits cortical spreading depression. Pain 2016; 157: 797-805
2016 Chen SP, Ayata C.* Spreading Depression in Primary and Secondary Headache Disorders. Current Pain and Headache Reports. 2016; 20(7):44
2016 Chen SP, Tolner EA,* Eikermann-Haerter K.* Animal models of monogenic migraine. Cephalalgia 2016; 36: 704-21
2015 Chen SP, Fuh JL, Lirng JF, Wang YF, Wang SJ.* Recurrence of Reversible Cerebral Vasoconstriction Syndrome: a Long-Term Follow-up Study. Neurology 2015; 84: 1-7
2013 Chen SP, Chung YT, Liu TY, Wang YF, Fuh JL,* Wang SJ.* Oxidative stress and increased formation of vasoconstricting F2-isoprostanes in patients with reversible cerebral vasoconstriction syndrome. Free Radical Biology & Medicine. 2013;61C:243-248
2012 Chen SP, Fuh JL, Lirng JF, Wang SJ.*Hyperintense vessels on FLAIR imaging in reversible cerebral vasoconstriction syndromes. Cephalalgia 2012; 32:271-8
2011 Chen SP, Fuh JL, Wang SJ.* Reversible cerebral vasoconstriction syndromes: Current and future perspectives. Expert Rev Neurother 2011; 11:1265-76
2010 Chen SP, Fuh JL, Wang SJ,* Chang FC, Lirng JF, Fang YC, Shia BC, Wu JC. Magnetic resonance angiography in reversible cerebral vasoconstriction syndromes. Annals of Neurology 2010; 67: 648-56
2010 Chen SP, Fuh JL, Wang SJ.* Reversible cerebral vasoconstriction syndromes- an under-recognised clinical emergency. Ther Adv Neurol Disord 2010; 3: 161-71.
2008 Chen SP, Fuh JL, Chang FC, Lirng JF, Shia BC, Wang SJ.* A transcranial color doppler study for reversible cerebral vasoconstriction syndromes. Annals of Neurology 2008; 63: 751-7
2006 Chen SP, Fuh JL, Lirng JF, Chang FC, Wang SJ.* Recurrent primary thunderclap headache and benign CNS angiopathy: spectra of the same disorder? Neurology. 2006;67:2164-9
年度 書名
2017 Chen SP, Theriot J, Brennan KC, Ayata C. Chapter 19. Animal model of migraine aura. Neurobiologic Basis of Migraine. 1st Edited by Turgay Dalkara and Michael A. Moskowitz. JohnWiley & Sons, Inc. 2017
2017 Chen SP, Wang SJ. Headaches due to vascular disorders. Modern Day Management of Headache- Questions and Answers. Edited by K Ravishankar, Randolph W Evans and Shuu-Jiun Wang. Jaypee- The Health Science Publisher, 2017
2016 Chen SP, Pascual J, Wang SJ. Chapter 25: Exertional and Sex Headache– In Michel Ferrari, Joost Haan, Andrew Charles, David Dodick, and Fumihiko Sakai (eds.), Oxford Textbook of Headache Syndromes (Oxford Textbooks in Clinical Neurology), Oxford Press, 2016
2016 Chen SP, Wang SJ. Chapter 15. Reversible cerebral vasoconstriction syndrome. International Neurology. 2nd 2016; DOI: 10.1002/9781118777329.ch15 (Publisher: Wiley-Blackwell)
獎項名稱 年度
108 年度吳大猷先生紀念獎 2019
疼痛學雜誌(Pain)最高引用次數學術論文獎 2018
國立陽明大學醫學系優良教師獎 2017
行政院退輔會台北榮民總醫院優良醫師「臨床教學績優醫師獎」 2016
國立陽明大學醫學系優良教師獎 2016
國立陽明大學醫學系優良教師獎 2015
行政院退輔會台北榮民總醫院優良醫師「醫師學術論文獎」 2011
台灣神經學會頭痛學組最佳壁報論文獎 2009
行政院退輔會台北榮民總醫院優良醫師「臨床教學績優醫師獎」 2009
台灣神經學會頭痛學組最佳壁報論文獎 2008
台灣神經學會頭痛學組最佳壁報論文獎 2006