年度	论文名称
2015	Cheng WH, Chen MC, Cheng IH*. Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer’s Disease. Scientific Reports 2015 Oct 15;5:15067. doi: 10.1038/srep15067 (Impact factor: 5.578;Rank: 8.93%)
2014	ChenWT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC and Cheng IH*.. G206D mutation of Presenilin-1 reduces Pen2 interaction, increases Aβ42/Aβ40 ratio and elevates ER Ca2+ accumulation. MOLECULAR NEUROBIOLOGY 2014; accept:. (Impact factor: 5.286;Rank: 15.94%)
2014	Lin YC, Wang JY, Wang KC, Liao JY, Cheng IH (2014) Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production. J Neurochem (accept) (IF :4.244)
2014	Fang YS, Tsai KJ, Chang YJ, Kao P, Woods R, Kuo PH, Wu CC, Liao JY, Chou SC, Lin V, Jin LW, Yuan H, Cheng IH, Tu PH, and Chen YR (2014) Full-Length TDP-43 Forms Toxic Amyloid Oligomers that are Present in Frontotemporal Lobar Dementia-TDP Patients. Nature Communication (Accept)(IF :10.742)
2013	Wu P-Y, Huang Y-Y, Chen C-C, Hsu T-T, Lin Y-C, Weng J-Y, Chien T-C, Cheng IH, Lien C-C (2013) Acid-Sensing Ion Channel-1a Is Not Required for Normal Hippocampal LTP and Spatial Memory. The Journal of Neuroscience 33:1828-1832.
2013	Huang C-W, Wang S-J, Wu S-J, Yang C-C, Huang M-W, Lin C-H, Cheng IH* (2013) Potential Blood Biomarker for Disease Severity in the Taiwanese Population With Alzheimer’s Disease. American Journal of Alzheimer's Disease and Other Dementias 28:75-83z
2012	Chen W-T, Hong C-J, Lin Y-T, Chang W-H, Huang H-T, Liao J-Y, Chang Y-J, Hsieh Y-F, Cheng C-Y, Liu H-C, Chen Y-R, Cheng IH* (2012) Amyloid-Beta (Aβ) D7H Mutation Increases Oligomeric Aβ42 and Alters Properties of Aβ-Zinc/Copper Assemblies. PLoS ONE 7:e35807
2012	Chu Y-F, Chen Y, Brown PH, Lyle BJ, Black RM, Cheng IH, Ou B, Prior RL (2012) Bioactivities of crude caffeine: Antioxidant activity, cyclooxygenase-2 inhibition, and enhanced glucose uptake. Food Chemistry 131:564-568.
2012	Chu Y, Chang W, Black R, Liu J, Sompol P, Chen Y, Wei H, Zhao Q, Cheng IH* (2012) Crude caffeine reduces memory impairment and amyloid β(1-42) levels in an Alzheimer's mouse model. Food Chemistry 135:2095-2102.
2011	Cheng IH*, Lin YC, Hwang E, Huang HT, Chang WH, Liu YL, Chao CY (2011) Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/Phosphatidylinositol 3-kinase signaling pathway. Neuroscience 183:178-188.
2011	Chen W-T, Liao Y-H, Yu H-M, Cheng IH, Chen Y-R (2011) Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+ on Amyloid-β Stability, Oligomerization, and Aggregation. Journal of Biological Chemistry 286:9646-9656
2011	Wu Y-Y, Cheng IH, Lee C-C, Chiu M-J, Lee M-J, Chen T-F, Hsu J-L (2011) Clinical Phenotype of G206D Mutation in the Presenilin 1 Gene in Pathologically Confirmed Familial Alzheimer's Disease. Journal of Alzheimer's Disease 25:145-150.
2010	Hong C-J, Tsai P-J, Cheng C-Y, Chou C-K, Jheng H-F, Chuang Y-C, Yang C-N, Lin Y-T, Hsu C-W, Cheng IH, Chen S-Y, Tsai S-J, Liou Y-J, Tsai Y-S (2010) ENU Mutagenesis Identifies Mice with Morbid Obesity and Severe Hyperinsulinemia Caused by a Novel Mutation in Leptin. PLoS ONE 5:e15333.
2009	Cheng JS, Dubal DB, Kim DH, Legleiter J, Cheng IH, Yu G-Q, Tesseur I, Wyss-Coray T, Bonaldo P, Mucke L (2009) Collagen VI protects neurons against A[beta] toxicity. Nat Neurosci 12:119-121.
2009	Chu Y-F, Brown PH, Lyle BJ, Chen Y, Black RM, Williams CE, Lin Y-C, Hsu C-W, Cheng IH* (2009) Roasted Coffees High in Lipophilic Antioxidants and Chlorogenic Acid Lactones Are More Neuroprotective than Green Coffees. Journal of Agricultural and Food Chemistry 57:9801-9808.
2009	Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce-Levie K, Cheng IH, Yu G-Q, Mucke L (2009) Neprilysin Overexpression Inhibits Plaque Formation But Fails to Reduce Pathogenic Aβ Oligomers and Associated Cognitive Deficits in Human Amyloid Precursor Protein Transgenic Mice. The Journal of Neuroscience 29:1977-1986.
2008	Sanchez-Mejia R, Newman J, Toh S , Yu GQ , Zhou Y , Scearce-Levie K,　Cheng IH, Gan L , Palop JJ, Bonventre J, Mucke L (2008) Phospholipase A2 reduction ameliorates cognitive deficits in mouse model of Alzheimer's disease. Nat. Neuroscience 11, 1311 - 1318
2007	Cheng IH, Scearce-Levie K, Palop J, Legleiterl J, Puoivali J, Lesne S, Ashe K, Muchowski P, & Mucke L. (2007) Accelerating Plaque Formation Reduces the Pathogenic Non-Fibrillar Amyloid-β Assembly in Arctic Mutant Alzheimer’s Disease Mouse Models. J. Biol. Chem. 282, 23818-23828
2007	Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L (2007) Reducing endogenous tau ameliorates amyloid-b induced deficits in an Alzheimer’s disease mouse model. Science. 316, 750-754.
2006	Ji Z-S, Mullendorff K, Cheng IH, Miranda RD, Huang Y, & Mahley RW (2006) Reactivity of Apolipoprotein E4 and Amyloid -βPeptide: Lysosomal Stability and Neurodegeneration. J. Biol. Chem. 281:2683-2692
2004	Cheng IH, Palop J, Esposito L, Bien-Ly N, Yan F, & Mucke L. Aggressive Amyloidosis in Mice Expressing Human Amyloid Peptides with the Arctic Mutation. Nature Medicine. 2004 10, 1190-1192.
2004	Sawyer SL, Cheng IH, Chai W,& Tye BK. (2004) Mcm10 and Cdc45 Cooperate in Origin Activation in Saccharomyces cerevisiae. J. Mol. Biol. 2004 340, 195-202.
2002	Cheng IH, Roberts LA, & Tye BK. Mcm3 Is Polyubiquitinated during Mitosis before Establishment of the Pre-replication Complex. J. Biol. Chem. 2002 277: 41706-41714.
2002	Lei M, Cheng, IH, Roberts, LA, McAlear, MA, & Tye BK. Two mcm3 Mutants Affect Different Steps in the Initiation of DNA Replication. J. Biol. Chem. 2002 277: 30824-30831.