叶 信显
生医技术平台
姓名 叶 信显
联络电话 +886-2-28267000 ext.67383
电子邮件 hhyeh@nycu.edu.tw
EDUCATION/TRAINING 英国曼彻斯特大学 转译医学所 影像科学学程 医学博士(2012年8月起更名为人口健康所)
简介
 

研究兴趣

分子癌症影像、脑神经影像、影像导引式治疗药物筛选、多重影像模组药物动力学、放射药物研发之转译医学
研究内容为利用新兴正子造影剂评估其在癌症与神经系统疾病的适用性。所应用的影像评估系统包括几个核心技术，如细胞摄取，细胞结合试验，动物组织萃取，数码式放射显影法，动态药物药效学与多重影像撷取与比较(PET, SPECT,Optical image,CT and MRI)。本研究团队将高阶影像技术与分析方法应用于数种癌症动物模式或神经退化性疾病之基因鼠;借此开发新型影像诊断造影剂或是应用活体影像高效率筛选开发中或老药新用之治疗药物成效。
 

Current activity

  • Neurodegenerative disease: Alzheimer's disease (AD) and Huntington’s Disease (HD)
  • Psychiatric disease: Post-traumatic stress disorder (PTSD)
  • Oncology: non small cell carcinoma lung cancer
年度 论文名称
2015 Hui-Ching Lin, Cheng-Ta Li, David Tat-Wei Tan, Chi-Wei Cheng, Ta-Kai Chou, Fan-Lin Kong, Tsung-Hsun Yu, Wen-Sheng Huang, Dong-Ping Su, Ren-Shyan Liu, Skye Hsin-Hsien Yeh*. Non-linear alteration of serotonin transport availability in posttraumatic stress disorder measured with 4-[18F]ADAM positron emission tomography. Current Molecular Imaging. 2015 Nov. DOI: 10.2174/2211555204 666151014224015
2015 Bonomi R, Mukhopadhyay U, Shavrin A, Yeh HH, Majhi A, Dewage SW, Najjar A, Lu X, Cisneros GA, Tong WP, Alauddin MM, Liu RS, Mangner TJ, Turkman N, Gelovani JG. Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain. PLoS One. 2015 Aug 5;10(8):e0133512. (IF:3.53, R=8/56=14%)
2015 Chi-Wen Yeh, Skye Hsin-Hsien Yeh, Feng-Shiun Shie, Wen-Sung Lai, Hui-Kang Liu, Tsai-Teng Tzeng, Huey-Jen Tsay and Young-Ji Shiao. Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 mice. Neurobiol Aging. 2015 Jul 18. pii: S0197-4580(15)00382-6. (IF:5.013 ,Ranking:16%).
2014 Whitehouse A, Doherty K, Yeh HH, Robinson AC, Rollinson S, Pickering-Brown S, Snowden J, Thompson JC, Davidson YS, Mann DM.Histone deacetylases (HDACs) in Frontotemporal Lobar Degeneration. Neuropathol Appl Neurobiol 2014 May 27. doi: 10.1111/nan.12153. [Epub ahead of print] (Impact factor: 4.873; Rank:45/255, 17.85%)
2014 Skye Hsin-Hsien Yeh, Ming-Hsien Lin, Fan-Lin Kong, Chi-Wei Chang, Li-Chung Hwang, Chien-Feng Lin, Jeng-Jong Hwang, Ren-Shyan Liu. Evaluation of inhibitory effect of recreational drugs on dopaminergic terminal neuron by PET and whole-body autoradiography. Biomed Res Int. 2014;2014:157923. http://dx.doi.org/10.1155/2014/157923 (Impact factor: 2.880; Rank: 50/159, 31.04%)
2014 Ya-Ju Hsieh, Luen Hwu, Chien-Chih Ke, Skye Hsin-Hsien Yeh, Chien-Feng Lin, Fu-Du Chen, Hsin-Ell Wang, Kang-Ping Lin, Ran-Chou Chen and R. Liu. Rational Design of a Triple Reporter Gene for Multimodality Molecular Imaging. Biomed Res Int. 2014;2014:605358. doi: 10.1155/2014/605358. Epub 2014 Apr 7. (Impact factor: 2.880; Rank: 50/159, 31.04%)
2014 Hsieh YJ, Hwu L, Chen YC, Ke CC, Chen FD, Wang HE, Lin KP, Yeh HH, Chang CW, Liu RS.. 21-Driven Multifusion Gene System for Evaluating the Efficacy of Histone Deacetylase Inhibitors by In Vivo Molecular Imaging and for Transcription Targeting Therapy of Cancer Mediated by Histone Deacetylase Inhibitor. J Nucl Med. 2014 Mar 17. [Epub ahead of print]. (SCI) (Impact factor: 7.022, Ranking: 0.9%)
2013 Skye Hsin-Hsien Yeh, Chien-Feng Lin, Fan-Lin Kong,Hsin-Ell Wang, Ya-Ju Hsieh, Juri G. Gelovani, Ren-Shyan Liu, Molecular Imaging of Nonsmall Cell Lung Carcinomas Expressing Active Mutant EGFR Kinase Using PET with [124I]-Morpholino-IPQA BioMed Research International, 2013.doi:10.1155/2013/549359. (SCI) (Impact factor: 2.880; Rank: 50/159, 31.04%)
2013 Hsin-Hsien Yeh, Daniel Young, Juri Gelovani Karl Herholz, David Mann. Histone deacetylase (HDAC) class II immunohistochemistry in human brains with Huntington’s disease. Brain Res. 2013 Apr 4;1504:16-24. doi: 10.1016/j.brainres. 2013.02.012. Epub 2013 Feb 16. (SCI) (Impact factor: 2.892; Rank: 126/251, 50.02%)
2013 Hsin-Hsien Yeh, Rainer Hinz, Suren Soghomonyan, Julius A. Balatoni, Uday Mukhopadhyay, Leo G. Flores, Asutosh Pal, Daniel Young, Hwan Jeong, Rajesh Uthamanthil, James Jackson, William Tong, Mei Tian, Mian M. Alauddin, Karl Herholz, Juri G. Gelovani. Quantification of HDAC activity in the forebrain, N.accumbens, and cerebellum in non-human primates using [18F]FAHA PET/CT and an optimized pharmacokinetic model. Neuroimage. 2013 Jan 1;64:630-9. doi: 10.1016/j.neuroimage.2012.09.019. Epub 2012 Sep 17. (SCI) (Impact factor: 6.252, Ranking: 3/116, 2.6%)
2013 Flores LG 2nd, Yeh HH, Soghomonyan S, Young D, Bankson J, Hu Q, Alauddin M, Huff V, Gelovani JG. Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using [18F]-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth. Mol Imaging Biol. 2013 Apr;15(2):175-85. doi: 10.1007/s11307-012-0588-5. (SCI) (Impact factor: 3.844, Ranking: 12.1%)
2012 Nashaat Turkman, Aleksander Shavrin, Vincenzo Paolillo, Hsin Hsien Yeh, Leo Flores, Suren Soghomonian, Brian Rabinovich, Andrei Volgin, Juri Gelovani, Mian Alauddin Synthesis and preliminary evaluation of [(18)F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB(2) receptor. Nucl Med Biol 2012, 39(4):593-600. (SCI) (Impact factor: 2.62, Ranking: 29.4%)
2011 Paolillo V, Yeh H H, Mukhopadhyay U, Gelovani JG, Alauddin MM. Improved detection and measurement of low levels of [18F]fluoride metabolized from [18F]-labeled pyrimidine nucleoside analogues in biological samples. 2011 Nucl Med Biol. Nov;38(8):1129-34. (SCI) (Impact factor: 2.62, Ranking: 29.4%)
2011 Yeh HH, Ogawa K, Balatoni J, Mukhapadhyay U, Pal A, Gonzalez-Lepera C, Shavrin A, Soghomonyan S, Flores L, Young D, Volgin AY, Najjar AM, Krasnykh V, Tong W, Alauddin MM, Gelovani JG. Molecular Imaging of Active Mutant L858R EGFR Kinase Expressing Non Small Cell Lung Carcinomas using PET/CT with [18F]F-PEG6-IPQA. 2011 Proc Natl Acad Sci USA, 108(4):1603-8. Epub 2011 Jan 10. (SCI) (Impact factor: 9.771, Ranking: 5.1%)
2010 Schwartz DL, Bankson J, Nishii R, Bidaut L, Yeh HH, He Y, Williams R, Volgin A, Lemos R, Titai-Kumar A, Oh J, Soghomonyan S, Mukhopadhyay, Allaudin M, Mushkudiani I, Kuno N, Krishnan S, Bornmann W, Lai SY, Powis G, Hazle J, Gelovani JG. HIF-1 dependent stromal adaptation to ischemia mediates in vivo tumor radiation resistance. 2010 Mol Cancer Res 2011 Mar;9(3):259-70. (SCI) (Impact factor: 2.620, Ranking: 23.0%)
2010 Ying Y, Ghosh P, Guo L, Pal A, Mukhapadhyay U, Peng Z, Yeh HH, Bertolini S, Flores LG, Young D, Volgin A, Soghomonyan S, Bornmann W, Logsdon C, Alauddin MM, Gelovani JG. Synthesis and Ex Vivo Autoradiographic Evaluation of Ethyl-beta-D:-galactopyranosyl-(1,4')-2'-deoxy-2'-[(18)F]fluoro-beta-D:-gluco- pyranoside A Novel Radioligand for Lactose-Binding Protein: Implications for Early Detection of Pancreatic Carcinomas with PET. 2010 Mol Imaging Biol Jun;13(3):536-46. (SCI) (Impact factor: 3.844, Ranking: 12.1%)
2009 Leo Garcia Flores, Susanna Bertolini, Hsin Hsin Yeh, Danel Young, Uday Mukhapadhyay, Ashutosh Pal, Yunming Ying, Andrei Volgin, Aleksandr Shavrin, Suren Soghomonyan,William Tong, William Bornmann, Mian M. Alauddin, Craig Logsdon, and Juri G. Gelovani. Detection of pancreatic carcinomas by imaging lactose-binding protein expression in peritumoral pancreas using [18F]fluoroethyl-deoxylactose PET/CT. 2009 PLoS One 4(11):e7977. (SCI) (Impact factor: 4.411, Ranking: 13.9%)
2008 Uday Mukhopadhyay, Suren Soghomonyan, Hsin Hsien Yeh, Leo G. Flores, Aleksandr Shavrin, Andrei Y. Volgin, Juri G. Gelovani, Mian M. Alauddin. N3-Substituted thymidine analogues: V. Synthesis and preliminary PET imaging of N3-[18F]fluoroethyl thymidine and 5 N3-[18F]fluoropropyl thymidine. 2008 Nucl Med Biol 35(6):697-705. (SCI) (Impact factor: 2.62, Ranking: 29.4%)
2004 Lin KJ, Yen TC, Wey SP, Hwang JJ, Ye XX, KY, Ting, Chen JC. Characterization of the binding sites of [123I]ADAM and the relationship to serotonin transporter in rat and mouse brains using quantitative autoradiography. 2004 J Nucl Med. 45, 673-681. (SCI) (Impact factor: 7.022, Ranking: 0.9%)
2004 Ye XX, Hwang JJ, Shieh JF, JC Chen, YT Chou, KY Tu, Wey SP, Ting G. In Vivo Quantification of bound [123I]ADAM to Serotonin Transporters in the Brains of Rabbits by SPECT. 2004 Nucl Med Biol. 31(8):995-1003. (SCI) (Impact factor: 2.62, Ranking: 29.4%)
2004 Ye XX, JC Chen, Liu RS, Wey SP, Lee JS, Ting G, Hwang JJ. Microautoraduography of [123I]ADAM in Mice Treated with Fluoxetine and Serotonin Reuptake Inhibitors. 2004 Nucl Med Bio. 31, 557-562. (SCI) (Impact factor: 2.62, Ranking: 29.4%)
2002 Lin KJ, Ye XX, Yen TC, Wey SP, Tzen KY, Ting G, Hwang JJ. Biodistribution study of [123I]ADAM in mice: correlation with whole body autoradiography. 2002 Nucl Med Biol. 29, 643-650. (SCI) (Impact factor: 2.62, Ranking: 29.4%)
年度 论文名称
2013 Skye Hsin-Hsien Yeh, Jin-Cai Chen, Zuo-Hao Tang, Hui-Jing Lin, Cheng-Ta Li3, Ta-Kai Chou, Wen-Sheng Huang, Dong-Ping Su, Ren-Shyan Liu. PET/CT with [18F]ADAM using a biomarker for quantification of SERT change in the brain of PTSD rat model. (Oral presentation) 2013 World Molecular Imaging Congress, Savannah, Georgia.
2013 Yu-Ning Tang, Skye Hsin-Hsien Yeh, Jin-Cai Chen, Chin-Wei Cheng, Hsin-Ell Wang, Irene Han-Juo Cheng, Ren-Shyan Liu. Longitudinal coupled-imaging Alzheimer's disease mouse model using [11C]PIB and [18F]FDG PET.(Poster presentation) 2013 World Molecular Imaging Congress, Savannah, Georgia.
2013 Skye Hsin-Hsien Yeh, Jin-Cai Chen, Zuo-Hao Tang, Hui-Jing Lin, Cheng-Ta Li3, Ta-Kai Chou, Wen-Sheng Huang, Dong-Ping Su, Ren-Shyan Liu. PET/CT with [18F]ADAM using a biomarker for quantification of SERT change in the brain of PTSD rat model. (Poster presentation) 2013 Society of Nuclear Medicine and Molecular Imaging, Vancouver, BC, Canada.
2013 Yu-Ning Tang, Skye Hsin-Hsien Yeh, Jin-Cai Chen, Chin-Wei Cheng, Hsin-Ell Wang, Irene Han-Juo Cheng, Ren-Shyan Liu. Longitudinal coupled-imaging Alzheimer's disease mouse model using [11C]PIB and [18F]FDG PET. (Poster presentation) 2013 Society of Nuclear Medicine and Molecular Imaging, Vancouver, BC, Canada.
2012 Hsin-Hsien Yeh, Mei Tian, Leo G. Flores, Daniel Young, Vincenzo Paolillo, Kun-eek Kil, Uday Mukhopadhyay, Julius A. Balatoni, Suren Soghomonyan, Asutosh Pal, Rajesh Uthamanthil, James Jackson, WilliamTong, Daniel Young, Mian M Alauddin, Juri G. Gelovani. PET/CT/MRI with [18F]TFAHA using an optimized pharmacokinetic model for Quantification of HDAC class II expression –activity in the brain in non-human primates (Oral presentation) 2012 World Molecular Imaging Congress, Dublin, Ireland.
2012 HsinHsienYeh, LeoG.Flores II, Suren Soghomonyan, Kuneek Kil,Vincenzo Paolillo, Uday Mukhopadhyay, Julius Balatoni, Asutosh Pal,Aleksandr Shavrin, Daniel Young, Mian Alauddin, William Tong, Juri G. Gelovani. Quantification of Suberoylanilide Hydroxamic and Valproic Acid-Induced Inhibition of HDAC Activity in Rat Brain using In Vivo PET/CT Imaging with HDAC Class IIa-Specific Radiotracers. (Oral presentation) 2012 World Molecular Imaging Congress, Dublin, Ireland.
2012 Hsin-hsien Yeh, Leo G. Flores, Daniel Young, Patrick J. Gillespie, Uday Mukhopadhyay, Asutosh Pal, Hwan Jeong, Nobuyoshi Fukumitsu, William Tong, Mian M Alauddin, Juri G. Gelovani. PET Imaging of Epigentic Mediated by HDACs in a Transgenic Mouse Model of Huntington’s Disease (Poster presentation) 2012 World Molecular Imaging Congress, Dublin, Ireland.
2012 HsinHsienYeh, Leo G. Flores II, Suren Soghomonyan, Kuneek Kil,VincenzoPaolillo,Uday Mukhopadhyay, Julius Balatoni, AsutoshPal, Aleksandr Shavrin, DanielYoung, Mian Alauddin,William Tong, JuriG. Gelovani. Quantification of Suberoylanilide Hydroxamic and Valproic Acid-Induced Inhibition of HDAC Activity in Rat Brain using In Vivo PET/CT Imaging with HDAC Class IIa-Specific Radiotracers. (Poster presentation) 2012 World Molecular Imaging Congress, San Diego USA.
2011 Hsin-Hsien Yeh, Mei Tian, Leo G. Flores, Daniel Young, Vincenzo Paolillo, Kun-eek Kil, Uday Mukhopadhyay, Julius A. Balatoni, Suren Soghomonyan, Asutosh Pal, Rajesh Uthamanthil, James Jackson, WilliamTong, Daniel Young, Mian M Alauddin, Juri G. Gelovani. PET/CT/MRI with [18F]TFAHA using an optimized pharmacokinetic model for Quantification of HDAC class II expression –activity in the brain in non-human primates (Oral presentation) 2011 World Molecular Imaging Congress, San Diego USA.
2011 Hsin-hsien Yeh, Leo G. Flores, Daniel Young, Patrick J. Gillespie, Uday Mukhopadhyay, Asutosh Pal, Hwan Jeong, Nobuyoshi Fukumitsu, William Tong, Mian M Alauddin, Juri G. Gelovani. PET Imaging of Epigentic Mediated by HDACs in a Transgenic Mouse Model of Huntington’s Disease (Oral presentation) 2011 World Molecular Imaging Congress, San Diego USA.
2011 Hsin-Hsien Yeh, Leo G. Flores II, Kun-eek Kil, Vincenzo Paolillo, Uday Mukhopadhyay, Julius Balatoni, Suren Soghomonyan, Aleksander Shavrin, Daniel Young, Mian Alauddin, William Tong, Juri G. Gelovani. Imaging epigenetic regulation in the rat brain mediated by HDACs class IIa Enzymes using PET/CT with 18F-TFAHA and 18F-DFAHA (Poster presentation) 2011 World Molecular Imaging Congress, San Diego USA.
2010 Hsin-Hsien Yeh, Rainer Hinz, Suren Soghomonyan, Julius A. Balatoni, Uday Mukhopadhyay, Leo G. Flores, Asutosh Pal, Hwan Jeong, Rajesh Uthamanthil, James Jackson, William Tong, Mei Tian, Mian M. Alauddin, Karl Herholz, Juri G. Gelovani. Quantification of HDAC activity in the forebrain, N.accumbens, and cerebellum in non-human primates using [18F]FAHA PET/CT and an optimized pharmacokinetic model. (Oral presentation) 2010 World Molecular Imaging Congress, Kyoto Japan.
2010 N. Fukumitsu, H. Yeh, L.G. Flores, S. Soghomonyan, U. Mukhopadhyay, D. Young, M.M. Alauddin, W. Tong, J.G. Gelovani. The Role of HDAC Activation in Chemotherapy-Induced Neurotoxicity and Protective Effects of HDAC Inhibitors in Rats Demonstrated using PET/CT with 18 F-FAHA and 18F-FDG (Oral presentation) 2010 World Molecular Imaging Congress, Kyoto Japan.
2010 Leo Garcia Flores, HsinHsien Yeh et. al., A Novel Model of Renal Tumor in Transgenic Mice: Characterization with Repetitive 18FDG PET and Dual Contrast-Enhanced CT Imaging. (Poster presentation) 2010 World Molecular Imaging Congress, Kyoto Japan.
2010 JJ Jong, HH Yeh et, al., Multi-Tracer Molecular-Genetic Imaging Reveals Distinct Areas of Coupling and Uncoupling of Blood Flow and HIF1 Signaling in a Rat Brain Glioma Model. (Poster presentation) 2010 World Molecular Imaging Congress, Kyoto Japan.
2008 Hsin Hsien Yeh, Suren Soghomonyan, Uday Mukhapadhya, Daniel Young, Leo G. Flores, Asutosh Pal, Kazuma Ogawa, Mian Alauddin, Raymond Gibson, Willian Tong, Juri G. Gelovani. Assessment of SAHA-induced Dose-Dependent Inhibition of HDACs Activity in the Rat Brain using In Vivo PET Imaging with 18FAHA. (Oral presentation) 2008 World Molecular Imaging Congress, France Nice.
2008 Hsin-Hsien Yeh, Daniel Young, Raymond Gibson, William Tong, Juri G. Gelovani. (2008) Imaging Expression-Activity of HDACs in the Awake Rat Brain using Autoradiography with [14C]AHA as a Prototype for [11C]AHA and PET. 2008 World Molecular Imaging Congress, France Nice.
2008 Hsin-Hsien Yeh, Suren Soghomonyan, Uday Mukhapadhyay, Daniel Young, Leo G. Flores, Asutosh Pal, Kazuma Ogawa, Raymond Gibson, Thomas Miller, Mian Alauddin, William Tong, Juri G.Gelovani. Determination of Dose-Dependent Inhibition of HDACs Activity induced by para-Fluoro-SAHA in the Rat Brain using In Vivo PET Imaging with [18F]FAHA. 2008 World Molecular Imaging Congress, France Nice.
2008 HsinHsien Yeh, Suren Soghomonyan, Uday Mukhapadhayay, Daniel Young, Leo G. Flores,Asutosh Pal, Kazuma Ogawa, Raymond Gibson, Mian Alauddin, William Tong, Juri G. Gelovani. Quantification of Valporic Acid-induced Dose-Dependent Inhibition of HDACs Activity in the Rat Brain using In Vivo PET Imaging with 18FAHA. 2008 World Molecular Imaging Congress, France Nice.
2008 Hsin Hsien Yeh, Ryuichi Nishii, Julius Balatoni, Asutosh Pal, Suren Soghomonyan, Leo Flores1, Andrei Volgin, Daniel Yang, Juri G. Gelovani. (2008) PET with [124I]I-PEG6-IPQA for Imaging Expression-Activity and Mutational Status of EGFR in Four Different Non Small Cell Carcinoma Xenografts in Mice. 2008 World Molecular Imaging Congress, France Nice.
2008 Hsin Hsien Yeh, Asutosh Pal, Julius Balatoni, Kazuma Ogawa, Leo Flores, Andrei Volgin, Daniel Yang, Juri G. Gelovani.Imaging Expression-Activity and Mutational Status of EGFR in Intracerebral Glioma Xenografts in Mice with [124I]I-PEG6-IPQA and PET. 2008 World Molecular Imaging Congress, France Nice.
2008 Hsin Hsien Yeh, Kazuma Ogawa, Julius Balatoni, Uday Mukhapadhyay, Asutosh Pal, Daniel Yang, Andrei Volgin, Mian Alauddin, Juri G. Gelovani. Imaging the Expression-Activity and Mutational Status of EGFR in Four Different Non Small Cell Carcinoma Xenografts in Mice using PET with [18F]F-PEG6-IPQA. . (oral presentation) 2008 World Molecular Imaging Congress, France Nice.
2007 U. Mukhopadhyay, S. Soghomonyan, A. Y. Volgin, H. H. Yeh, L. G Flores, J. G. Gelovani and M. M. Alauddin. Synthesis and preliminary PET imaging of N3-[18F]fluoroethyl thymidine and N3-[18F]fluoropropyl thymidine. 2007 Joint Molecular Imaging Conference, Providence, Rhode Island, USA.
2007 Ryuichi Nishii, Uday Mukhopadhyay, Hsin Yeh, Suren Soghomonyan, Andrei Volgin, Mian Alauddin, William Tong, Juri Gelovani. PET imaging of histone deacetylase activity in a rat brain using 6-([18F]-fluoroacetamide)-1-hexanoicanilide ([18F]-FAHA). 2007 Joint Molecular Imaging Conference, Providence, Rhode Island, USA
2007 Ryuichi Nishii, Uday Mukhopadhyay, Hsin Yeh, Suren Soghomonyan, Andrei Volgin, Mian Alauddin, William Tong, Juri Gelovani. 2007 Non-invasive imaging of histone deacetylase activity in human breast carcinoma xenografts in rats using positron emission tomography (PET) with [18F]-FAHA. 2007 Joint Molecular Imaging Conference, Providence, Rhode Island, USA
2006 David Schwartz, Sunil Krishnan, Norihito Kuno, Ioseb Mushkudiani, Andrei Volgin, Hsin Hsien Yeh, Yi He, Suren Soghomonyan, Uday Mukhopadhyay, Mian Alauddin, Shujun Shentu, Garth Powis, Juri Gelovani Molecular-Genetic In Vitro and In Vivo Imaging of HIF-1 Signaling Response to Radiation and Targeted Inhibition. 2006 Joint Molecular Imaging Conference, Hilton Waikoloa Village on the Big Island of Hawaii
2006 Ryuchi Nishii, Asutosh Pal, Suren Soghomonyan, Julius Balatoni, Ioseb Mushkudiani, Hsin Hsien Yeh, Uday Mukhopadhyay, Andrei Volgin, Aleksander Shavrin, David Maxwell, William Tong, Mian Alauddin, William Bornmann, Juri Gelovani Molecular Imaging of Different EGFR Kinase Mutant NSCL Carcinomas with [124I]-Mipqa PET for Prediction of Responsiveness to EGFR Kinase Inhib. 2006 Joint Molecular Imaging Conference, Hilton Waikoloa Village on the Big Island of Hawaii .
2003 Ye XX, Hwang JJ, Chen JC, Shieh JF, YT Chou. SPECT Imaging of Serotonin Transporters in the Brains of Rabbits by [123I]ADAM. 2003 Annual Meeting of the Society of Nuclear Medicine, New Orleans, USA.
2002 Ye XX, Hwang JJ, Hsieh JF, Chen JC. In Vivo quantification of bound [123I]ADAM in serotonin transporters in the brains of rabbits by SPECT. (oral presentation) 2002 Annual Meeting of the Society of Nuclear Medicine, Los Angles, USA.
2002 Lin KJ, Ye XX, Yen TC, et al. Biodistribution study of [123I]ADAM in mice: correlation to whole body autoradiography. 2002 Annual Meeting of the Society of Nuclear Medicine, Los Angeles, USA.
2001 Ye XX, Hwang JJ, Chen JC, Shieh JF. In Vivo quantification of bound 123I-ADAM in serotonin transporters in rabbit by SPECT. 2001 Annual Meeting of the Society of Nuclear Medicine, Taipei, Taiwan.
2001 Lin KJ, Yen TC, Ye XX, et al. The biodistribution of I-123 ADAM in mouse with macroautoradiography. 2001 Annual Meeting of the Society of Nuclear Medicine, Taipei, Taiwan.
年度 书名
2019 Skye Hsin-Hsien Yeh, Chun-Kai Fang, Jeng-Jomg Hwang. Effects of Club Drugs on Dopaminergic and Serotonergic Systems: Use of [18F]FDOPA, [99mTc]TRODAT-1 and [I*]ADAM. The Neuropathology Of Drug Addictions And Substance Misuse, Kings College London (in press)
奖项名称 年度 记事
Travel Award 2013
Selected Abstracts for Highlight Lecture 2012 • PET/CT/MRI with [18F]TFAHA using an optimized pharmacokinetic model for quantification of HDAC class II expression-activity in the brain of non-human primates.
• PET/CT/MRI with [18F]TFAHA using an optimized pharmacokinetic model for quantification of HDAC class II expression-activity in the brain of non-human primates.
Overseas Research Students Award 2012
Performance Award 2011
Student Travel Award 2011
Overseas Research Students Award 2011
Student Travel Award 2010
Overseas Research Students Award 2010
Performance Award 2009
Overseas Research Students Award 2009
Performance Award 2008
Student Travel Award 2008
Graduate Scholarship 2008
Graduate Scholarship 2007
Graduate Scholarship 2006
Graduate Scholarship 2005
The Best Annual Investigation 2001 Title：Biodistribution Study of [123I] ADAM in Mice: correlate to whole body autoradiography